Friday, August 6, 2010

Microarray results from IVF #7


Sorry for the long silence - and thanks much to those who have checked in on me, both on this blog and by email. I'm finding the depot lupron extremely difficult to tolerate. Feeling pretty miserable with it, honestly. It's knocked me for a major loop. I just took the second dose a week ago, so am at least at the halfway mark. Here's hoping the endometriosis is disappearing as I type. I can't wait to be done with this stage of things and to start feeling like myself again.

We've received the microarray results and wanted to share with you all. The news is fairly unbelievable - as in, it is so good that I almost cannot process the information. Will, too, is incredulous.

Out of our seven blasts that were tested from this latest cycle, FIVE were chromosomally normal. We also had one no result, which could also be normal. So only one confirmed abnormal.

Incredible.

Also - and this makes my and Will's hearts rest a bit easier - four of the five normals this time are day 6 blasts. The other is a day 7 (across both cycles, ALL of my day 7s have been normal, crazy, huh?)

So...with two CCRM cycles under our belts, we have totalled eight chromosomally normal embryos. Four that developed on time and without in vitro maturation.

Bottom line, we've got multiple tries here in case we don't get pregnant with our first transfer, which is something I never thought I would be able to say. Not something Dr. Schl. thought we would ever be able to say either. He told us back at the one day work up that he would let us cycle, but that we should expect to learn that we needed an egg donor. We cycled that first time really for emotional closure. Then threw in an extra cycle to boot.

And here we are several months later with EIGHT priceless normals.

Way to knock it out of the park, CCRM. I think you guys may have just changed the course of our lives.

Now if only I can survive the rest of these lupron days.

Mo


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63 comments:

  1. Wow! That really is unbelievable in the best possible way. Makes being on that Lupron a bit more bearable though...

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  2. The thing lost my comment :*(

    Anyway congratulations. You have me thinking and wondering if we should go to CCRM as well despite the added cost of travel.

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  3. Wow, I'm de-lurking to say congratulations! Exciting results.

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  4. INCREDIBLE NEWS!!!!!!!!!!!! I am so happy about the embryo results!! I am sorry about the depot lupron cycle - I haven't ever done it, but it doesn't sound like a picnic. Hang in there - I think it's time to say that there is a bright light at the end of this insane journey!!
    Best of luck - fabulous~

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  5. I've said it before, but - HURRAHHHH!!!!!!

    SO seriously, unbelievably happy for you both (all!) Can't wait for Thor to have 8 little pseudo-cousins to play with every time we visit the city.

    Honestly, such amazingly wonderful news and I CAN'T WAIT for your next non-Lupron step.

    Yay!

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  6. I am sooooo happy for you guys! I have been following you for some time, but I don't comment often. These are GREAT news!!! I think you might have something here {smiling}... You're halfway done with Lupron, look at it that way, it makes it easier. I was on Lupron for a long time as well, and I had plenty of side effects... I know what you mean :)

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  7. Oh, Mo!!! So absolutely thrilled to hear this. Woohoo!! Doing the happy dance! :-)

    Sorry to hear about the lupron misery. Blech!

    Big hug to you, and sending loving energy to the Denver eight.

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  8. Mo, that is fantastic! I'm so thrilled for you and Will.

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  9. Wow. I just sat down to catch up on my reading and look at the good news you have to share! This is incredibly exciting and I can't wait for you to be underway.

    Wow. Who would have thunk it, you know? Congrats for having the tenacity and perseverance to change course. Wishing you an abundance of good luck (and hoping the depot lupron days will soon be over and the treatment a success).

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  10. Congratulations -- what happy news. Hoping the lupron starts treating you a little better, or at least that the rest of your time with it passes quickly.

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  11. Awesome news Mo! I'm so excited for you. You've definitely got a great collection of blasts there!

    I hope the Depot Lupron misery passes quickly.

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  12. Mo, that is fabulous. Seriously, it's really wonderful that you have all of these perfectly wonderful embryos hanging around for you to use. (I'm having a vision of a van full of little mos or wills.)

    On the depot lupron, I'm sorry it has sucked so much; I thought the regular lupron was horrific, so I am impressed you have the will to live, let alone type an update. And the icky horribleness of the NYC summer I'm sure hasn't helped you feel any better....

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  13. I was so worried for you guys!!! And look at your results !!!!!!! The game has changed my friend. Enjoy as much as you can through the depot lupron gloom. But know that this is another deal entirely. Am speechless. And VERY happy for you xxx

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  14. AWESOME, AWESOME NEWS!!!!! Hoping the first transfer will be THE ONE! Best of luck...

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  15. I'm covered in goosebumps, that is awesome!! So happy for ya'll and praying for nothing but the best from here on out!

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  16. WOAH!!! Yeah, CCRM did great, but kudos to you guys too for being proactive and taking such good care of yourselves. I hope the rest of your stay in Lupron land is short.

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  17. Oh Mo, I am just so happy for you both! It is truly bringing tears to my eyes. I'm so glad you guys chose to head out to CCRM, and so glad they were able to give you some great news!

    Hang in there with the DL. Yes, it sucks (it really sucks!!), but if it can make a nice place for one (or more??) of those nice normal embies for 9 months, then it is worth it.

    Hooray! :)

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  18. Marvelous news!! I remember a few months ago when you weren't sure you wanted to go through with another retrieval....and here you are, with a wonderful, wonderful result. I'm full of smiles for you.

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  19. What great news! To have so many normals is just mind boggling! Are you keeping up with the CCRM cocktail of supplements still?

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  20. This is sooo fabulous!!!! I am so happy for you - wow!!!! I can't wait to keep following your story.

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  21. WOW!!! I am so happy to read this- talk about hitting the homerun! I was wondering how you were doing, sorry the lupron is not being kind
    :( but like you said, you are 1/2 way done....with eight normal gorgeous embryos to work with!!!Woohooo! Looking forward to this fall for you and Will...Fabulous!

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  22. So excited to see your great news! Glad you decided to do that extra cycle.

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  23. Wow now that is some of the best news I've heard in a long time in the IF blogosphere! Here's to hoping that those embryos bring you a baby or two! Congrats and best wishes as you continue the dreaded loopyron!

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  24. That's awesome news!!!! So, forgive my ignorance on this type of cycle, but when will you have an FET?!?!?! I see you're halfway through the lupron, and like I said, I don't know anything about the type of things you're doing (I was IVF/ICSI), so thought I'd throw it out there for you to answer! Congrats!

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  25. All I can say is
    YAAAHHHH for Mo and Will :)!!!!!!!!!!!!!!!!!
    FINALLY!

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  26. Such wonderful news! I am over the moon for you two!

    I am so sorry that the lupron is trying hard to kick your butt. Sending hugs with the congratulations to help with some of the misery...

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  27. Squee!!

    I know this is totally crazy from a stranger, but I've been having dreams about a successful cycle for you guys. Keeping my fingers crossed!

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  28. What great news!!! My heart sings for you!

    Rest well on this positive result, let yourselves smile and enjoy the moment (as much as you can while on that crazy Lipton shit).

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  29. Woohoo!!!! Am so happy for you, that reassurance that you can keep trying with all those frosties waiting for you - absolutely brilliant!

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  30. So so awesome. Can't wait to see where this road leads! :)

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  31. This is fantastic news! WOW! They really did knock it out of the park! WOOHOO

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  32. Yahhh!!!! :)

    That's fantastic news! I'm so happy for you both! Sucks that the Lupron is kicking you in the tush though. Like you said you are 1/2 way there. And hopefully this is the last time you need to be on Lupron for awhile! (like 9 months) :)

    All my very best to you!
    ks

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  33. Absolutely amazing!! CCRM is the best!

    Congratulations!

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  34. And THAT is why CCRM doesn't have to accept insurance if they don't want to!

    They may not hit a homerun for everyone but I am a firm believer that if anyone can get a gal KTFU, it's them.

    Can't wait to follow you through your FET(s) and to the land of BFP!

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  35. HOT DAMN!

    That is the best possible news Mo, congratulations!!!!! Amazing and
    wonderful
    stupendous
    outstanding
    miraculous
    hopeful
    dazzling
    delightful

    love to you and Will from
    a
    very very very happy kate.

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  36. Wow, just wow!! So happy you're happy!

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  37. I have been checking in regularly to see if there was any news. What fantastic news this is! I am so happy for you both! I wish you all the best! Congratulations!

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  38. Hot damn (the "hot" part was an homage to the lupron). Simply outstanding news. Isn't it just beautiful when hope rears its pretty little head? (My boy was the result of a 6 day blast, for what it's worth.) Yippee for Mo and Will and some damn good normals!

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  39. I am so pleased to hear of your great microarray results! Awesome news! Sorry the Depot Lupron is so hard on you though.
    Congrats on the great news and the wonderful opportunity that lies ahead!

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  40. A MAZ ING! I am so happy for you Mo!

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  41. U.N.B.E.L.I.E.V.A.B.L.E

    Dude, you must be floatin' on cloud 9 ... the game *has* changed!

    WOOT WOOOT!!!

    I so can't wait for your sticky BFP!

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  42. That is wonderful, amazing, fantastic news! I am so happy for you and Will! What a great job CCRM has done! Gosh, I am so glad you guys decided to do another fresh cycle when you did. I'm sorry the lupron is making you miserable. I can't wait for October!

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  43. WOW! Such terrific news--so very happy for you and Will!!!

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  44. That is awesome, so great!

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  45. Keep hoping! Sometimes that's all we can do.

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  46. I have to say, your story isn't unusual at all. If I had a dollar for every story in which a couple went through tens of thousands and multiple IVF's with abysmal results but wound up with chromosomally sound embryos at CCRM, I might have paid for my last cycle at CCRM with it ;)

    Their lab is second to none, period. That's the distinguishing factor and you've now become proof of that.

    You have quite a large number of munchkins on ice.

    Wishing you the very best on the transfer and what's sure to be subsequent pregnancy!

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  47. I'm so happy for you and Will! I held my breath when I saw your post title, and it took me a moment to work up the courage to read it. Feeling very relieved for you, and hoping the DL misery ends soon...

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  48. Fantastic! What a haul! Am SO pleased for you!

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  49. That's great news! I'm so very happy for you and hope this is the one that really works for all of you!

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  50. I'm glad to read that you've got some chances finally. I'm really rooting for you still.

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  51. Soooooo gonna follow your journey.

    You are an inspiration of persistence, hope, humor and devotion. You will be terrific parents.

    How are you doing today?

    Write me anytime. I am genuinely interested in hearing from you.

    ivfgirl@gmail.com

    Yours in IVF,
    Beth

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  52. So very happy for you, and so glad that you are more than halfway through your depot lupron, and that much closer to your FET! Cheering hard for you from here!

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  53. I have not been around much at all, but this is incredible news to come back to. Congrats on such wonderful results. You are getting closer!
    Hope you are feeling better soon!

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  54. Great news!! How are you doing today?

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  55. Hey -- It's been a while since you posted and I wanted to check in and see if the lupron had totally made you crazy or if you were doing ok. Hope you are doing well!

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  56. Any more updates for us? How is the lupron going?

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  57. I am so glad you got this good news!

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  58. Hoping you are ok- I miss you here!
    xox
    kate

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  59. Just wanted to check in on you to see how you are doing. Hope things are still on track! Update when you can. Thinking of you.

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